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Augmentation with buspirone: a review

K V Harvey1, R Balon

  • 1Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, Michigan, USA.

Annals of Clinical Psychiatry : Official Journal of the American Academy of Clinical Psychiatrists
|September 1, 1995
PubMed
Summary
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Buspirone, a serotonin 5-HT 1A partial agonist, shows potential as an adjunctive treatment for various psychiatric disorders. This review explores its efficacy in augmenting other psychotropic medications.

Area of Science:

  • Psychopharmacology
  • Neuroscience

Background:

  • Buspirone is an FDA-approved anxiolytic medication.
  • It functions as a serotonin (5-HT) 1A partial agonist.
  • Investigated for efficacy in depression, panic disorder, OCD, and schizophrenia.

Purpose of the Study:

  • To review existing literature on buspirone's potential as an augmenting agent.
  • To evaluate its utility in combination with other psychotropic medications.

Main Methods:

  • Literature review of clinical trials and studies.
  • Analysis of research supporting buspirone's augmentation role.

Main Results:

  • Several trials suggest buspirone's utility in augmenting psychotropic treatments.

Related Experiment Videos

  • Evidence supports its use across various psychiatric conditions.
  • Conclusions:

    • Buspirone demonstrates promise as an augmenting agent in psychiatric pharmacotherapy.
    • Further research may solidify its role in treatment-resistant cases.