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Updated: Sep 15, 2026

Establishment and Characterization of UTI and CAUTI in a Mouse Model
Published on: June 23, 2015
Abstract:
The study covers eighty-seven women, aged 21 to 68 years, presenting chronic recurrent cystitis. In 53 of the total number (60.92 percent) no evidence of intravesical obstruction is found. In the remainder 34 (39.08 percent), following urethral calibration and urodynamic investigations, direct and indirect data pointing to urethral stricture are established. Urethrotomy is done in thirteen women, and dilatation of the urethra (up to 30)-in twenty-one. After the manipulations described, a six-month antibiotic prophylaxis against urinary infection relapse is conducted. It is demonstrated that urethrotomy and dilatation of the urethra lead to normalization of the urodynamic indicators and subjective miction improvement. Within a year, one to several cystitis recurrences are recorded in all women documented.
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