Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ewing's sarcoma

R Vlasak1, F H Sim

  • 1Department of Orthopedic Oncology, Mayo Clinic/Mayo Foundation Rochester, Minnesota 55905, USA.

The Orthopedic Clinics of North America
|July 1, 1996
PubMed
Summary
This summary is machine-generated.

Significant advancements in treating children's Ewing's sarcoma have dramatically improved outcomes. Aggressive chemotherapy and surgery have boosted 5-year survival rates for this rare bone cancer from 10% to over 70%.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reconstruction of the hip after resection of periacetabular oncological lesions: a systematic review.

The bone & joint journal·2018
Same author

Ice Hockey Injuries.

The Physician and sportsmedicine·2016
Same author

Evaluation and management of unicompartmental osteoarthritis: role of arthroscopy in upper tibial osteotomy.

Orthopedics·2014
Same author

Pigmented villonodular synovitis.

Orthopedics·2014
Same author

Synovial sarcoma.

Orthopedics·2014
Same author

Radial nerve palsy associated with humeral fractures.

Orthopedics·2014
Same journal

New Technologies.

The Orthopedic clinics of North America·2026
Same journal

Recent Innovations and Applications of Custom 3D Printed Cages for Critical Bone Defects in Foot and Ankle Surgery.

The Orthopedic clinics of North America·2026
Same journal

Application of New Technologies: Patient-specific Instrumentation and Artificial Intelligence in the Field of Foot and Ankle.

The Orthopedic clinics of North America·2026
Same journal

Robotic-Assisted Latissimus Dorsi Transfers Around the Shoulder.

The Orthopedic clinics of North America·2026
Same journal

Blood Flow Restriction Therapy for the Upper Extremity: An Emerging Adjunct for Patient Recovery and Rehabilitation.

The Orthopedic clinics of North America·2026
Same journal

The Emerging Roles for 3 Dimensional Printing in Orthopedics: Applications, Evidence, and Future Directions.

The Orthopedic clinics of North America·2026
See all related articles

Area of Science:

  • Pediatric Oncology
  • Skeletal System Malignancies
  • Cancer Treatment Research

Background:

  • Ewing's sarcoma is the second most frequent primary malignant bone tumor in children.
  • Recent decades have seen substantial progress in the multidisciplinary management of Ewing's sarcoma.
  • Survival rates for this pediatric bone cancer have seen remarkable improvement.

Purpose of the Study:

  • To review recent advancements in the diagnosis, staging, and treatment of Ewing's sarcoma.
  • To highlight the impact of multidisciplinary care on patient survival.
  • To discuss the evolving role of chemotherapy and surgery in managing pediatric bone tumors.

Main Methods:

  • Review of current literature and treatment protocols for Ewing's sarcoma.

Related Experiment Videos

  • Analysis of survival data reflecting treatment efficacy over the past 25 years.
  • Discussion of diagnostic and staging methodologies in pediatric oncology.

    • Main Results:

    • Aggressive chemotherapy regimens have significantly increased 5-year survival rates, rising from 10% to over 70%.
    • The importance of surgical intervention for achieving local tumor control has become increasingly recognized.
    • Multidisciplinary approaches have demonstrably enhanced treatment outcomes for children with Ewing's sarcoma.

    Conclusions:

    • The integrated approach combining chemotherapy and surgery has revolutionized Ewing's sarcoma treatment.
    • Continued research and refined multidisciplinary strategies are crucial for further improving survival in pediatric bone cancer.
    • Advances in diagnosis and staging contribute to more effective and personalized treatment plans.