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Langerhans' cell histiocytosis

M C Velez-Yanguas1, R P Warrier

  • 1Department of Pediatric Hematology/Oncology, Louisiana State University Medical Center and Children's Hospital, New Orleans 70118, USA.

Langerhans' Cell Histiocytosis, formerly known as Histiocytosis X, and its related syndromes (i.e., eosinophilic granuloma, Hand-Schuller-Christian disease, and Letterer-Siwe disease) are briefly reviewed. The biology, clinical manifestations, and treatment options of the localized, single form and the disseminated, multisystem form are also discussed.

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