Related Experiment Videos
Prenatal detection of two different monosomic cell lines by chorionic villus sampling
1Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
Prenatal Diagnosis
|February 1, 1996
Summary
This study reports the first prenatal case of mosaicism with two distinct monosomic cell lines, including monosomy 21 and monosomy X, identified in chorionic villus cells. This rare finding occurred in a fetus with cystic hygroma and growth retardation.
Area of Science:
- Genetics
- Prenatal Diagnosis
- Cytogenetics
Background:
- Mosaicism, the presence of two or more cell lines with different genotypes, can occur during early development.
- Prenatal diagnosis of chromosomal abnormalities is crucial for assessing fetal health.
- Chorionic villus sampling (CVS) is a common method for first-trimester prenatal genetic testing.