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Twelfth-nerve palsy. Analysis of 100 cases
1Department of Neurology, Los Angeles County/University of Southern California Medical Center, USA.
Archives of Neurology
|June 1, 1996
Summary
Hypoglossal nerve palsy, often a sign of serious illness, is frequently caused by tumors or trauma. This condition, also known as twelfth-nerve palsy, rarely leads to full recovery, indicating a poor prognosis.
Area of Science:
- Neurology
- Otolaryngology
Background:
- Hypoglossal nerve palsy (twelfth-nerve palsy) is a neurological condition affecting tongue movement.
- Understanding its causes and characteristics is crucial for diagnosis and management.
Purpose of the Study:
- To delineate the etiology and clinical presentation of hypoglossal nerve palsy.
- To analyze the outcomes associated with this condition.
Main Methods:
- Retrospective review of clinical data over 26 years.
- Analysis of patient cases from a large public hospital setting.
Main Results:
- Tumors, primarily malignant, were the leading cause (49 cases).
- Trauma, specifically gunshot wounds, was the second most common cause (12 cases).
- Other significant causes included stroke, hysteria, multiple sclerosis, surgery, Guillain-Barré neuropathy, and infections.
Conclusions:
- Hypoglossal nerve palsy is often an ominous indicator of underlying pathology.
- Complete or near-complete recovery occurred in only 15% of patients, suggesting a poor prognosis.