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Occlusion of the neonatal patent ductus arteriosus with a simple retrievable device: a feasibility study
1Department of Cardiology, Children's Hospital, University of Bonn, Adenauerallee 119, D-5300, Bonn 1, Germany.
Purpose:
To examine the feasibility of transvenous placement of a new memory-shaped, small, retrievable coil that has a smaller-caliber delivery system than currently available devices, for closure of the patent ductus arteriosus (PDA).
Methods:
Through 4 or 5 Fr vascular sheaths and 4 or 5 Fr end-hold catheters, the coils were delivered and placed in piglets (n = 10) with PDA. The coils were made from 0.018" (0.46 mm) or 0.028" (0.71 mm) stainless steel guidewire. Mounted for delivery, the new device has the appearance of a conventional guidewire. This neonatal PDA model was created without major surgery or drugs by stenting the ductus arteriosus.
Results:
The memory-shaped coils were easily delivered. Coils not optimally placed were retrieved and repositioned. Occlusion of the ductus arteriosus as early as a half-hour after delivery was shown angiographically and confirmed by histopathology.
Conclusion:
This new, small-caliber, simple device was found to be effective for closure of the PDA in this animal model. Longer-term observations are needed.
