Incomplete data sets: coping with inadequate databases
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Updated: Nov 5, 2026

Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering
Published on: November 22, 2019
1U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition (HFS-500), Washington, DC 20204, USA.
Abstract:
Three problems arise in handling numerical values in databases: bad data, missing data, and sloppy data. The effects of bad data are mitigated by using statistical subterfuges such as robust statistics or outlier removal. Missing data are replaced by creating a substitute through interpolation or by using statistics appropriate to unbalanced designs. Sloppy, semiquantitative data are relegated to innocuous positions by using nonparametric, rank, or attribute statistics. These techniques are illustrated by the telephone directory, a database of carcinogenicity test results, and a database of precision parameters derived from method performance (collaborative) studies.
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