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A comparison between ketorolac and diclofenac in laparoscopic sterilization
1Department of Anaesthesia and Intensive Care, Prince of Wales Hospital, Chinese University of Hong Kong.
European Journal of Anaesthesiology
|November 1, 1995
Summary
Intramuscular ketorolac and diclofenac showed limited effectiveness for post-laparoscopic sterilization pain. Both drugs were well-tolerated, but diclofenac caused more injection site pain.
Area of Science:
- Anesthesiology
- Pharmacology
- Pain Management
Background:
- Post-operative pain management is crucial for patient recovery.
- Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used for pain relief.
Purpose of the Study:
- To compare the efficacy and tolerability of ketorolac versus diclofenac for post-operative pain after laparoscopic sterilization.
Main Methods:
- A randomized trial involving 50 women undergoing laparoscopic sterilization.
- Participants received either intramuscular diclofenac 75 mg or ketorolac 30 mg pre-operatively.
- Pain scores were assessed at multiple time points, with additional analgesia administered as needed.
Main Results:
- Both ketorolac and diclofenac demonstrated limited effectiveness in controlling post-operative pain.
- Pain scores were similar between the two groups throughout the study period.
- Injection site pain was reported more frequently in the diclofenac group (12 vs. 3 patients).
Conclusions:
- Intramuscular diclofenac and ketorolac are relatively ineffective for managing pain following laparoscopic sterilization.
- While equally tolerated, diclofenac was associated with a higher incidence of injection site discomfort.