[Analytical evaluation of an automated hematologic analyzer: Cell Dyn 3500]

In this study we evaluated the analytical performances of the Cell Dyn 3500, an automated hematology analyzer that provides the electronic and optical detection of leukocyte count and the complete cell counts in samples of whole blood. The protocol included evaluation of complete blood count and differential leukocyte count parameters, using the ICSH and the NCCLS H20-A protocols. Technical performances with regards, to linearity, carry over, precision and stability were quite well acceptable; the accuracy showed a good agreement between Cell Dyn 3500 and instruments used in our laboratory for the major hematologic indices and a good correlation for neutrophils, lymphocytes and eosinophils compared with the manual count.