Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Beyond unilateral neglect

E Bisiach1, L Pizzamiglio, D Nico

  • 1Dipartimento di Psicologia, Università di Torino, Italy.

Brain : a Journal of Neurology
|June 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Calorie-restriction treatment mitigates the aging in rat liver model.

Biogerontology·2025
Same author

From movement to thought and back: a review on the role of cognitive factors influencing technological neurorehabilitation.

Functional neurology·2020
Same author

Effect of different music genres on gait patterns in Parkinson's disease.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2019
Same author

The nine circles of EBM hell.

Functional neurology·2019
Same author

From paper to informatics: the Post Soft Care-App, an easy-to-use and fast tool to help therapists identify unmet needs in stroke patients.

Functional neurology·2019
Same author

Imaging of underground cavities with cosmic-ray muons from observations at Mt. Echia (Naples).

Scientific reports·2017
Same journal

Disrupted WWOX-MYC interplay impairs neurogenesis in human brain organoids.

Brain : a journal of neurology·2026
Same journal

SMPD4 deficiency disrupts indirect neurogenesis and neuronal migration in gyrencephalic cortex.

Brain : a journal of neurology·2026
Same journal

Retinal hyper-reflective foci link retinal and cortical pathology in paediatric multiple sclerosis.

Brain : a journal of neurology·2026
Same journal

Two scripts, two pathways: dorsal-ventral biases in post-stroke kana-kanji agraphia.

Brain : a journal of neurology·2026
Same journal

Blood cytotoxic natural killer-like CD8 + CD94+ T cells migrate to the brain and predict multiple sclerosis severity.

Brain : a journal of neurology·2026
Same journal

Time to reconsider risk for psychosis?

Brain : a journal of neurology·2026
See all related articles

Patients with left neglect misplace line endpoints leftward, challenging current theories. Optokinetic stimulation worsened this spatial representation disorder, suggesting a fundamental issue with horizontal spatial anisometry.

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Clinical Neurology

Background:

  • Unilateral neglect is a neurological disorder affecting spatial awareness.
  • Current models struggle to explain neglect in tasks beyond simple line bisection.
  • Left neglect patients exhibit specific spatial misjudgments.

Purpose of the Study:

  • To investigate spatial representation in left neglect patients using a novel endpoint-setting task.
  • To explore the effects of optokinetic stimulation (OKS) on spatial judgment in neglect.
  • To propose a new framework for understanding unilateral neglect.

Main Methods:

  • Participants with left neglect were asked to set endpoints of a line based on its midpoint.
  • The task was performed under normal conditions and during leftward optokinetic stimulation (OKS).

Related Experiment Videos

  • Endpoint placement errors were analyzed to assess spatial representation biases.

    • Main Results:

    • Left neglect patients consistently misplaced endpoints leftward, even in this new task.
    • Optokinetic stimulation (OKS) exacerbated the leftward endpoint misplacement.
    • The results contradict existing explanations for unilateral neglect.

    Conclusions:

    • Unilateral neglect may stem from a disorder of horizontal spatial anisometry (unequal spatial representation).
    • Interventions like OKS might alleviate neglect symptoms without correcting the underlying spatial representation deficit.
    • This suggests a need to re-evaluate the mechanisms of spatial neglect.