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Updated: Oct 16, 2026

Preparation of Synaptic Plasma Membrane and Postsynaptic Density Proteins Using a Discontinuous Sucrose Gradient
Published on: September 3, 2014
[Specific proteins of synaptic structures]
Abstract:
The article deals with the data concerning localization, properties and functions of specific proteins of nerve endings, especially in the synaptic vesicles and synaptic membranes, as well as concerning their metabolism. In the fractions of the synaptic vesicles and synaptic membranes simple and conjugated proteins (glycoproteids) typical of these high-specialized structures only are localized. Acid polypeptides, contractile proteins and neurospecific proteins of S-100, 14-3-2 type and glycoproteids are such specific proteins of the studied structures. Their possible function in the mechaninsm of secretion and circulation of mediators in synapses is discussed.
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