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Intraventricular supratentorial tumors in children
P Tortori-Donati1, M P Fondelli, A Rossi
1Servizio di Neuroradiologia, Istituto Scientifico, Giannina Gaslini, Genova, Italy.
Summary
Childhood intraventricular supratentorial tumors are rare. This review covers common types like choroid plexus tumors and subependymal giant cell astrocytomas, focusing on their characteristics and diagnosis.
Area of Science:
- Pediatric neuro-oncology
- Neurosurgery
- Pathology
Background:
- Intraventricular supratentorial tumors are uncommon in pediatric patients.
- Tumor classification distinguishes intraventricular origins (e.g., choroid plexus) from glial neoplasms of the ventricular wall.
Purpose of the Study:
- To review the most common intraventricular supratentorial neoplasms in childhood.
- To discuss choroid plexus tumors (papillomas, carcinomas) and subependymal giant cell astrocytomas.
Main Methods:
- Literature review of common pediatric intraventricular tumors.
- Discussion of histopathology, clinical presentation, and diagnostic imaging (Contrast-enhanced CT).
Main Results:
- Choroid plexus papillomas are frequent congenital tumors in infants.
- Choroid plexus carcinoma is a rare, invasive, high-grade malignancy with metastatic potential.
- Subependymal giant cell astrocytomas are typically benign (Grade I) glial tumors, often associated with tuberous sclerosis.
Conclusions:
- Accurate histopathological classification is crucial for treatment and prognosis.
- Contrast-enhanced CT plays a vital role in differentiating tumors like subependymal giant cell astrocytomas from nodules.