Hepatitis B virus-associated nephropathy: 17 year progression from onset to end-stage renal failure

Hepatitis B virus-associated nephropathy (HB nephropathy) was first described in 1971. There have been few reports on the long-term prognosis in children with HB nephropathy. A case is reported here of a child who presented with symptoms of acute glomerulonephritis at 12 years of age and progressed to end-stage renal failure 17 years after the clinical onset, in spite of the seroconversion of HB virus by formation of HBe antibody.