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The sign of Leser-Trelat associated with esophageal carcinoma
1First Department of Internal Medicine, School of Medicine, Iwate Medical University, Morioka, Japan.
The American Journal of Gastroenterology
|April 1, 1996
Abstract:
A 79-year-old woman was admitted to our hospital with complaints of dysphagia and multiple verrucous papules that had developed over the previous year. The diagnosis of esophageal carcinoma was based on upper gastrointestinal radiography and endoscopic examination with biopsy. The clinical syndrome was consistent with the sign of Leser-Trelat associated with esophageal carcinoma. Although radiation therapy and chemotherapy were undertaken, the patient died 8 months later because of the sign of Leser-Trelat in association with squamous cell esophageal carcinoma.