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Trace elements in chronic sinusitis

M Onerci1, S Kus

  • 1Department of Otolaryngology Head and Neck Surgery, Hacettepe University Faculty of Medicine, Ankara, Turkey.

European Archives of Oto-Rhino-Laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
|January 1, 1995
PubMed
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This study investigated trace element levels in patients with chronic sinusitis. Copper levels were significantly lower in patients compared to healthy individuals, suggesting a potential link between copper deficiency and chronic sinusitis.

Area of Science:

  • Immunology
  • Nutritional Science
  • Otolaryngology

Background:

  • Trace elements are vital for immune function.
  • Serum trace element levels may decrease during chronic infections.
  • Chronic sinusitis is a prevalent condition with complex pathophysiology.

Purpose of the Study:

  • To evaluate serum zinc (Zn), magnesium (Mg), and copper (Cu) levels in patients with chronic sinusitis.
  • To compare these levels with those of a healthy control group.
  • To explore potential correlations between trace elements and chronic sinusitis.

Main Methods:

  • Serum samples were collected from 43 patients diagnosed with chronic sinusitis.
  • Serum samples were also collected from 20 age- and sex-matched healthy volunteers.

Related Experiment Videos

  • Levels of Zn, Mg, and Cu were measured using appropriate laboratory techniques.

    • Main Results:

    • All measured trace elements (Zn, Mg, Cu) were within the normal range for patients.
    • Copper (Cu) levels were significantly lower in the chronic sinusitis patient group compared to the control group.
    • No significant differences were observed for Zinc (Zn) and Magnesium (Mg) levels between the groups.

    Conclusions:

    • While serum zinc and magnesium levels were comparable, significantly lower copper levels were observed in patients with chronic sinusitis.
    • The underlying reasons for the reduced copper levels in chronic sinusitis require further investigation.
    • This finding suggests a potential role for copper in the context of chronic sinusitis, warranting further research.