Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Primary bone malignancies in children

M Hahn1, J P Dormans

  • 1Children's Hospital of Philadelphia, PA 19104, USA.

Current Opinion in Pediatrics
|February 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Validation of interaction databases in psychopharmacotherapy].

Der Nervenarzt·2017
Same author

Preoperative breast MR Imaging in patients with primary breast cancer has the potential to decrease the rate of repeated surgeries.

European journal of radiology·2017
Same author

Repeated surgeries in invasive lobular breast cancer with preoperative MRI: Role of additional carcinoma in situ and background parenchymal enhancement.

European journal of radiology·2017
Same author

Aberrant splicing of the tumor suppressor CYLD promotes the development of chronic lymphocytic leukemia via sustained NF-κB signaling.

Leukemia·2017
Same author

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin·2017
Same author

Changes of the bone structure after cap resurfacing arthroplasty of the humeral head.

Orthopaedics & traumatology, surgery & research : OTSR·2017
Same journal

For health, for beauty, or both? navigating trends as adolescent clinicians.

Current opinion in pediatrics·2026
Same journal

Childhood sleep disorders: practical management for the pediatrician.

Current opinion in pediatrics·2026
Same journal

Advanced therapies in management of pediatric inflammatory bowel disease.

Current opinion in pediatrics·2026
Same journal

Artificial intelligence in pediatric endoscopy for hereditary polyposis syndromes: promises and challenges.

Current opinion in pediatrics·2026
Same journal

Hormonal acne therapies in pediatrics.

Current opinion in pediatrics·2026
Same journal

Clinical implementation of artificial intelligence in adolescent mental healthcare.

Current opinion in pediatrics·2026
See all related articles

Pediatric bone cancer survival has improved due to advances in chemotherapy, radiation, imaging, and limb-sparing surgery. Molecular genetics also enhances diagnosis and understanding of osteosarcoma and Ewing's sarcoma.

Area of Science:

  • Pediatric Oncology
  • Skeletal Tumors
  • Surgical Oncology

Background:

  • Primary bone malignancies in children present unique challenges in diagnosis and treatment.
  • Significant advancements in the last decade have led to improved outcomes for pediatric bone cancer patients.

Purpose of the Study:

  • To highlight the evolution of treatment strategies for pediatric primary bone tumors.
  • To emphasize the impact of recent advances in diagnostics, surgical techniques, and adjuvant therapies.

Main Methods:

  • Review of current treatment modalities including chemotherapy, radiotherapy, and surgical resection.
  • Discussion of reconstruction techniques following limb-sparing surgery (allografts, prostheses).
  • Integration of advances in molecular genetics for improved tumor understanding and diagnosis.

Related Experiment Videos

Main Results:

  • Improved disease-free survival rates attributed to multimodal treatment approaches.
  • Enhanced diagnostic accuracy through advanced imaging (MRI) and molecular genetics.
  • Successful limb-sparing surgeries with various reconstruction options leading to better functional outcomes.

Conclusions:

  • Multidisciplinary care and innovative treatment strategies have significantly improved prognosis for pediatric bone cancers.
  • Continued research in molecular genetics and surgical techniques promises further advancements in treating osteosarcoma and Ewing's sarcoma.