[The ensemble organization of the sensorimotor cortex in ontogeny]
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Updated: Nov 5, 2026

In Vivo Visualization of Spontaneous Activity in Neonatal Mouse Sensory Cortex at a Single-Neuron Resolution
Published on: November 21, 2023
Abstract:
Examination of sensomotor zone of the human brain cortex in human subjects (from newborns up to 20 year-olds) with yearly intervals revealed the presence of all neuroglia-vascular ensembles components without any relationship in composition by the moment of birth. Significant increase of the cortical layers and sublayers thickness, connected with growth of the volume of all type neurons and development of dendritic-axonic networks, vessels and glia were noted. Stair-like groups of neurons are present by the moment of birth, and so called racemose groups, the composition of which is diverse in different fields form by the age of three when vertical and horizontal contacts system grows more complicate and the astrocyte glia differentiates. The size of pyramidal neurons (Betz cells included), fusiform and stellate neurons increases by the age of six. By 10-12 years intraensemble, interensemble and transcortical contacts attain the high level of development. By 16-18 years ensemble organization of the cortex reaches the level, characteristic to adults in main parameters of its architectonics.
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