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Emerging roles of nitric oxide in inflammation
1Cancer Research and Treatment Center, University of New Mexico Health Sciences Center, Albuquerque, USA.
Hospital Practice (1995)
|July 15, 1996
Abstract:
The short-lived, highly reactive NO radical arises in two ways: 1) a rapidly triggered process well suited for homeostatic fine-tuning of blood pressure and 2) a prolonged high-level production best suited for microbicidal activity. Roles in vascular "leakiness" and leukocyte extravasation are also emerging. Continued investigation may yield new therapies addressing individual facets of inflammation.