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[Chronic pancreatitis: conservative therapy]
1Klinik für Gastroenterologie, Hepatologie und Infektiologie Universitäts-Klinikum, Magdeburg.
Therapeutische Umschau. Revue Therapeutique
|May 1, 1996
Summary
Chronic pancreatitis management focuses on pain relief, managing exocrine insufficiency with pancreatic enzymes, and treating diabetes. Complete alcohol avoidance is crucial for a better disease course.
Area of Science:
- Gastroenterology
- Internal Medicine
Background:
- Chronic pancreatitis is primarily linked to prolonged alcohol abuse.
- Key clinical features include chronic pain, steatorrhea, and potential diabetes mellitus development.
Purpose of the Study:
- To outline the management principles for chronic pancreatitis.
- To emphasize the importance of alcohol cessation and systematic treatment approaches.
Main Methods:
- Treatment strategies involve drug therapy, symptomatic pain management, and pancreatic enzyme replacement.
- Octreotide use is limited to specific cases due to unproven general efficacy.
- Pancreatogenic diabetes management mirrors Type I diabetes mellitus treatment.
Main Results:
- Complete alcohol avoidance significantly improves the disease prognosis.
- Pancreatic enzyme substitution effectively alleviates exocrine insufficiency symptoms.
- Careful attention to enzyme dosage and preparation is essential.
Conclusions:
- Effective chronic pancreatitis management requires a systematic approach tailored to its variable presentation.
- Surgical intervention may be necessary for complications like pseudocysts.