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Updated: Aug 4, 2026

Mouse Pneumonectomy Model of Compensatory Lung Growth
Published on: December 17, 2014
[The pathogenesis of hypoventilation in the operated lung]
Abstract:
The content of immunocompetent cells, activity of lipid peroxidation processes, function of the surfactant system, and levels of prostacyclin and thromboxane were studied in 9 patients with resected lungs in the perioperative period separately for the intact and operated on lung. The function of immunocompetent cells deteriorated in both lungs after surgery. The levels of albumin and thromboxane were increased in the bronchoalveolar washings from the lung operated on reliably more than in those from intact lung, and the surface active characteristics deteriorated. Eight patients developed hypoventilation of the operated on lung in the postoperative period.
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