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A review of renal scarring in children

J R MacKenzie1

  • 1Department of Radiology, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK.

Nuclear Medicine Communications
|March 1, 1996
PubMed

Insights

Children with urinary tract infections need imaging to check for kidney damage. A 99Technetium-dimercaptosuccinic acid (99mTc-DMSA) scan is the most sensitive method for detecting renal scarring and preventing kidney disease.

Area of Science:

  • Pediatric Nephrology
  • Diagnostic Imaging
  • Nuclear Medicine

Background:

  • Urinary tract infections (UTIs) in children often necessitate diagnostic imaging to evaluate for renal scarring.
  • The optimal imaging modality for detecting renal scarring post-UTI remains a subject of debate among medical professionals.

Purpose of the Study:

  • To review and compare the advantages and disadvantages of various diagnostic imaging techniques used in children following a urinary tract infection.
  • To establish a consensus on the most effective imaging method for identifying renal scarring and predicting risk.

Main Methods:

  • Comprehensive literature review of available studies on diagnostic imaging for pediatric UTIs.
  • Comparative analysis of intravenous urography, ultrasound, and 99mTc-DMSA scintigraphy.

Main Results:

  • The 99mTc-DMSA scan is identified as the most sensitive diagnostic tool for detecting existing renal scarring.
  • 99mTc-DMSA scintigraphy effectively highlights kidneys at risk of developing scarring.

Conclusions:

  • Early and widespread adoption of 99mTc-DMSA scintigraphy is recommended for children with UTIs.
  • Increased utilization of DMSA scans may reduce the incidence of end-stage renal disease in pediatric populations.

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