Clinical factors promoting the development of allergic contact dermatitis

Some clinically recognized factors promoting allergic contact dermatitis include the colour and structure of the skin, disorders affecting blood-vessels, the microclimate, friction and implantation. A survey is given according to the areas of the body which are influenced more or less by one of these factors. The area around an ulcer is especially easily sensitized by many applied chemicals. The part played by the microclimate in sensitization mainly depends on the amount of sweat and the hyperhydration of the skin. Some recent publications concerning friction and implantation are reviewed.