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Case report: polymyositis-induced myoglobinuric acute renal failure

V Thakur1, J DeSalvo, H McGrath

  • 1Department of Medicine, Louisiana State University School of Medicine, New Orleans 70112, USA.

Insights

Polymyositis can cause myoglobinuric acute renal failure, a rare but serious complication. Early diagnosis and prompt treatment are crucial for a better prognosis despite historical challenges.

Area of Science:

  • Nephrology
  • Rheumatology
  • Internal Medicine

Background:

  • Polymyositis is an idiopathic inflammatory myopathy characterized by symmetrical proximal muscle weakness.
  • Myoglobinuric acute renal failure is a rare but severe complication of polymyositis, often associated with rhabdomyolysis.
  • The prognosis for polymyositis-associated acute renal failure has historically been poor.

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