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Practolol peritonitis

R E Lee, H Baddeley, A J Marshall

    Clinical Radiology
    |March 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Practolol-induced peritonitis can cause small bowel changes like dilation and delayed transit. Barium examinations may suggest this diagnosis, prompting a review of beta-blocker therapy history.

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    Area of Science:

    • Gastroenterology
    • Pharmacology

    Background:

    • Practolol is a beta-blocking agent.
    • Peritonitis is inflammation of the peritoneum.
    • Drug-induced conditions can mimic other diseases.

    Purpose of the Study:

    • To identify characteristic radiographic findings of practolol-induced peritonitis.
    • To highlight the diagnostic utility of small bowel barium examinations.
    • To emphasize the importance of considering drug history in unexplained gastrointestinal symptoms.

    Main Methods:

    • Retrospective review of nine patients with practolol-induced peritonitis.
    • Analysis of small bowel barium examinations for specific findings.
    • Correlation of findings with patient history of practolol use.

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    Main Results:

    • Barium studies showed fixation, dilation, and separation of small bowel loops.
    • Delayed small intestinal transit was observed in affected patients.
    • Symptoms occurred up to one year after discontinuing practolol.

    Conclusions:

    • Small bowel barium examination can suggest practolol-induced peritonitis.
    • A history of prolonged beta-blocker therapy should be investigated.
    • Gastrointestinal symptoms post-practolol warrant barium examination.