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Hypertension in adult American Indians. The Strong Heart Study
1Medlantic Research Institute, Washington, DC 20010-2933, USA.
Insights
Hypertension prevalence in American Indians varied by region, with rates similar to the general US population in some areas. Aggressive treatment is crucial due to links with diabetes and cardiovascular disease.
Area of Science:
- Cardiovascular epidemiology
- American Indian health
- Hypertension research
Background:
- Cardiovascular disease is a leading cause of death for American Indians.
- Hypertension prevalence, awareness, and control are understudied in this population.
- The Strong Heart Study investigates cardiovascular disease risk factors in American Indians.
Purpose of the Study:
- To determine the prevalence of hypertension in American Indians.
- To examine correlates of blood pressure, including diabetes, obesity, age, and albuminuria.
- To understand the relationship between blood pressure and obesity/hyperinsulinemia in this group.
Main Methods:
- Longitudinal study of 2703 women and 1846 men from 13 American Indian tribes.
- Baseline clinical examination (July 1989-January 1992) included interviews and physical exams.
- Measurements included oral glucose tolerance tests and three blood pressure readings.
Main Results:
- Hypertension prevalence in Arizona and Oklahoma was similar to US national data (NHANES III).
- Prevalence was significantly lower in South/North Dakota participants (P < .0001).
- Blood pressure correlated with diabetes (P < .0001), age (P < .0001), and albuminuria (P < .0001), but not strongly with obesity or insulin.
Conclusions:
- Hypertension prevalence varies among American Indian populations.
- Blood pressure in American Indians appears less influenced by obesity and hyperinsulinemia than in other groups.
- Aggressive hypertension management is vital for reducing morbidity and mortality associated with diabetes and cardiovascular disease in American Indians.
Abstract:
Hypertension is a primary risk factor for cardiovascular disease in the United States. Although cardiovascular disease is the leading cause of death among American Indians, the prevalence of hypertension, its awareness and control, and its association with other cardiovascular disease risk factors and physiological variables have not been well studied in this population. The Strong Heart Study is a longitudinal study of cardiovascular disease and its risk factors in American Indians. Participants (2703 women and 1846 men) were members of 13 tribes in central Arizona, southwestern Oklahoma, and regions of South and North Dakota. At least 1500 individuals between 45 and 74 years of age participated from each center in a baseline clinical examination conducted between July 1989 and January 1992. The examination consisted of a personal interview and physical examination that included an oral glucose tolerance test and three consecutive blood pressure measurements. This study reports data from the baseline examination on the prevalence of hypertension and correlates of blood pressure. Results indicated that despite the high frequency of diabetes and obesity, prevalence rates of hypertension in Arizona and Oklahoma were similar to those in the US population in the Third National Health and Nutrition Examination Survey (NHANES III), and rates among South/North Dakota participants were significantly lower (P < .0001). Blood pressure was higher in individuals with diabetes (P < .0001) and was significantly correlated with age (P < .0001) and albuminuria (P < .0001) but only weakly related to obesity. There was no independent relation between blood pressure and insulin. Blood pressure seems to be less affected by obesity and hyperinsulinemia in American Indians compared with other populations. Nevertheless, hypertension should be aggressively treated and controlled in American Indians because it is a known precursor to morbidity and mortality associated with diabetes and cardiovascular disease.
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