Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Small perfusion defects in suspected pulmonary embolism

P D Stein1, J W Henry, A Gottschalk

  • 1Henry Ford Heart and Vascular Institute, Detroit, Michigan 48202-2691, USA.

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|August 1, 1996
PubMed
Summary

Perfusion lung scans with 1-3 small subsegmental defects indicate a very low probability of pulmonary embolism (PE). More than 3 defects suggest a low probability of PE, aiding diagnosis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sequential BCR::ABL1 evaluation during dose de-escalation in peripheral blood is more predictive of TFR success than single assessment at dose de-escalation in either peripheral blood or bone marrow.

Leukemia·2026
Same author

Epidural needle insertion : A large registry analysis.

Der Anaesthesist·2018
Same author

Sci-Thurs PM: Delivery-12: Correction and calibration of megavoltage cone-beam CT images for the calculation of the dose of the day.

Medical physics·2017
Same author

[Beginning of continuous wound infusion with local anesthetics : With special emphasis on the contributions from Walter Capelle and Ewald Fulde].

Der Anaesthesist·2017
Same author

Tunnelling of thoracic epidural catheters is associated with fewer catheter-related infections: a retrospective registry analysis.

British journal of anaesthesia·2016
Same author

Evidence of an association between brain cellular injury and cognitive decline after non-cardiac surgery.

British journal of anaesthesia·2015

Area of Science:

  • Radiology
  • Nuclear Medicine
  • Diagnostic Imaging

Background:

  • Pulmonary embolism (PE) diagnosis relies on imaging.
  • Perfusion lung scans are used to detect PE.
  • Small subsegmental defects require careful interpretation.

Purpose of the Study:

  • To evaluate the diagnostic value of 1-3 vs. >3 small subsegmental defects on perfusion lung scans for acute pulmonary embolism (PE).

Main Methods:

  • Utilized data from the Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED) study.
  • Included patients with suspected acute PE and normal chest radiographs.
  • Focused on perfusion lung scans with small subsegmental defects (<25% of a segment).

Main Results:

Related Experiment Videos

  • Perfusion scans with 1-3 small subsegmental defects had a 1-3% positive predictive value for PE.
  • Perfusion scans with >3 small subsegmental defects had an 11-17% positive predictive value for PE.

Conclusions:

  • 1-3 small subsegmental defects on perfusion scans indicate a very low probability (<10% PPV) of PE.
  • >3 small subsegmental defects indicate a low probability (<20% PPV) of PE.
  • These findings help stratify PE risk in patients with equivocal scans.