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Sequence analysis of the human DNA flanking sites of human immunodeficiency virus type 1 integration
1Department of Microbiology and Immunology, University of North Carolina at Chapel Hill 27599-7295, USA.
Journal of Virology
|September 1, 1996
Abstract:
Human immunodeficiency virus type 1 (HIV-1) tagged with the Escherichia coli supF gene has been used to clone integrated HIV-1 proviruses. Sequence analysis of the 600 to 800 bp of human DNA adjacent to 29 clones revealed a propensity for HIV-1 to integrate near the Alu class of human repetitive elements.