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Related Experiment Videos

Mortality in prostate cancer

A Krongrad1, H Lai, S H Lamm

  • 1Department of Urology, University of Miami School of Medicine, Florida, USA.

The Journal of Urology
|September 1, 1996
PubMed
Summary
This summary is machine-generated.

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Prostate cancer treatment is linked to reduced mortality. The benefit of treatment for prostate cancer patients increased significantly between 1973 and 1990, indicating improved care over time.

Area of Science:

  • Oncology
  • Epidemiology
  • Public Health

Background:

  • Prostate cancer remains a significant health concern globally.
  • Understanding treatment efficacy and mortality trends is crucial for patient outcomes.

Purpose of the Study:

  • To assess the association between prostate cancer treatment and mortality.
  • To determine if this association changed over calendar time.

Main Methods:

  • Analysis of 146,979 prostate cancer patients from 1973-1990 (SEER data).
  • Utilized survival analysis and multivariate proportional hazards modeling.
  • Estimated relative risk for disease-specific and overall mortality.

Main Results:

  • Advanced age, black race, high tumor stage, and lack of treatment were associated with higher mortality.

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  • A significant decrease in the relative risk of mortality was observed in treated patients from 1973 to 1990.

    • Conclusions:

    • Prostate cancer treatment is associated with lower disease-specific and overall mortality.
    • Findings suggest potential biological differences in elderly and black men.
    • Improvements in care patterns from 1973-1990 likely contributed to reduced mortality.