Can gastric pouch as orthotopic bladder replacement be used in adults?
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Updated: Nov 5, 2026

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
Published on: August 9, 2012
1Urological Clinic, University Hospital Zurich, Switzerland.
Purpose:
We studied orthotopic bladder replacement with stomach in adults with bladder carcinoma, with emphasis on possible subsequent complications, such as incontinence, the dysuria or hematuria syndrome, ulceration or perforation. We attempted to prove a correlation between stabilized urine pH and hypergastrinemia.
Materials And Methods:
Since June 1992, 19 men between 53 and 73 years old underwent surgery for nonmetastatic grade 3 bladder carcinoma according to our new technique.
Results:
Patient outcome was good. Possible complications are discussed, such as incontinence, hypergastrinemia and ulcerations.
Conclusions:
Sufficient pouch capacity is achieved with our proposed operative technique. Urine pH must be monitored to prevent possible ulcerations and perforations.
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