Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Operations for gastric ulcer: a long-term study

M P McDonald1, T A Broughan, R E Hermann

  • 1Department of General Surgery, The Cleveland Clinic Foundation, Ohio, USA.

The American Surgeon
|August 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hsp90 inhibitor induces nuclear translocation of HSF1 predominantly in hippocampal CA1 region.

Molecular psychiatry·2017
Same author

Targeted deletion of GD3 synthase protects against MPTP-induced neurodegeneration.

Genes, brain, and behavior·2017
Same author

A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer's mouse model via an HSF1-mediated mechanism.

Molecular psychiatry·2016
Same author

Abnormal vibrissa-related behavior and loss of barrel field inhibitory neurons in 5xFAD transgenics.

Genes, brain, and behavior·2014
Same author

Supercontinuum spatial modulation spectroscopy: detection and noise limitations.

The Review of scientific instruments·2013
Same author

A single intramuscular injection of rAAV-mediated mutant erythropoietin protects against MPTP-induced parkinsonism.

Genes, brain, and behavior·2012
Same journal

Complete Response of Merkel Cell Carcinoma to Immunotherapy and Single-Fraction Radiotherapy Following Severe COVID-19 Infection: A Case Report and Review of Immune Mechanism.

The American surgeon·2026
Same journal

Perioperative Acute Myocardial Infarction in Non-Cardiac Operations: A National Analysis.

The American surgeon·2026
Same journal

Outcomes of Completion Cholecystectomy: Association With Patient Comorbidity in a National Database.

The American surgeon·2026
Same journal

Building the Conversation: Editorial Stewardship in Contemporary Surgical Publishing.

The American surgeon·2026
Same journal

Musculoskeletal Pain in Surgeons on Operating Days.

The American surgeon·2026
Same journal

Splenectomy During Cytoreductive Surgery: Marker of Surgical Burden or Independent Predictor of Morbidity?

The American surgeon·2026
See all related articles

Surgical management of benign gastric ulcers shows excellent long-term results across various procedures. Gastric resection or vagotomy with pyloroplasty offer comparable outcomes for these stomach conditions.

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Clinical Outcomes

Background:

  • Benign gastric ulcers require effective surgical management.
  • Long-term outcomes of different surgical approaches have been historically varied.
  • Patient factors and ulcer characteristics influence surgical decision-making.

Purpose of the Study:

  • To evaluate the long-term results of surgical operations for benign gastric ulcers.
  • To compare the efficacy of different surgical techniques.
  • To identify factors influencing operative mortality and morbidity.

Main Methods:

  • A retrospective study of 349 patients operated on between 1950-1979.
  • Follow-up of patients for a mean of 11.8 years.
  • Analysis of surgical procedures including gastric resection, vagotomy, pyloroplasty, and wedge excision, based on ulcer type, suspected malignancy, urgency, and patient health.

Related Experiment Videos

Main Results:

  • Overall mortality was 6.9%, significantly higher for emergency operations (32.5%) versus elective (3.6%).
  • Age and cardiovascular disease impacted mortality and morbidity.
  • All surgical approaches demonstrated equivalent long-term results, with 92% excellent to good outcomes and a 4% ulcer recurrence rate.

Conclusions:

  • Vagotomy, pyloroplasty, and wedge excision is a viable alternative to gastric resection for benign gastric ulcers.
  • Adding vagotomy to gastric resection does not significantly improve long-term results.
  • Surgical approach selection should consider patient-specific factors for optimal outcomes in gastric ulcer management.