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Putative linkage between HLA class I polymorphism and the susceptibility to malignant melanoma
M Ichimiya1, M Muto, Y Hamamoto
1Department of Dermatology, Yamaguchi University School of Medicine, Japan.
The Australasian Journal of Dermatology
|May 1, 1996
Abstract:
Human leukocyte antigen (HLA) frequencies in 67 melanoma patients were compared to 120 controls in Japan. The frequency of HLA-B13 was increased in melanoma patients compared to controls and was particularly common in nodular melanoma HLA-B61 was decreased in melanoma patients. Almost 50% of acral lentiginous melanoma patients expressed HLA-B51 compared to 0% of nodular melanomas.