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Updated: Aug 15, 2026

A Standardized Method for Measuring Internal Lung Surface Area via Mouse Pneumonectomy and Prosthesis Implantation
Published on: July 26, 2017
[Morphological studies of the lungs in experimental burns]
Ts Boshnakova1, V Nankova, L Sedmakova
1Department of Pathological Anatomy, Higher Medical School, Sofia.
Abstract:
The authors studied light- and electronmicroscopically the lungs of 20 rats after experimental burns in closed space. Twenty one histological parameters were evaluated. Two mechanisms of quickly developed fatal outcome were established--asphyxia and acute injury of shock lung. Electronmicroscopically there was an increased secretion of surface active materials and degenerative changes in the alveolar epithelium and capillary endothelium. Carbon particles found in the upper respiratory tract were considered as signs of vitality.

