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Updated: Aug 10, 2026

Fluorescence in situ hybridization (FISH) Protocol in Human Sperm
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Fluorescence in situ hybridization (FISH) Protocol in Human Sperm

Published on: September 1, 2009

[Fluorescence in situ hybridization in prenatal diagnosis. First experiences]

E Tardy1, A Tóth, K Hajdu

  • 1Haynal Imre Egészségtudományi Egyetem, Budapest, Szülészetei és Nögyógyászati Klinika.

Orvosi Hetilap
|March 10, 1996
PubMed
Summary

Non-radioactive in situ hybridization shows promise for prenatal screening of chromosomal abnormalities. Further research is needed to establish routine protocols for cytogenetic analysis.

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In situ hybridization (ISH) is a technique used to detect and localize specific DNA or RNA molecules in cells, tissue, or tissue sections using a labeled probe. The technique was first used in 1969 for the investigation of nucleic acids. It is currently an essential tool in scientific research and clinical settings, especially for diagnostic purposes.
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