Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Brain natriuretic peptide]

G La Villa1, C Lazzeri, C Fronzaroli

  • 1Istituto di Medicina Interna, Università degli Studi di Firenze.

Annali Italiani Di Medicina Interna : Organo Ufficiale Della Societa Italiana Di Medicina Interna
|October 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

RoboticAssisted (RATS) versus Video-Assisted (VATS) lobectomy: A monocentric prospective randomized trial.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2023
Same author

Prognostic bioindicators in severe COVID-19 patients.

Cytokine·2021
Same author

A Metabolic Intravascular Platform to Study FDG Uptake in Vascular Injury.

Cardiovascular engineering and technology·2020
Same author

Prematurity, ventricular septal defect and dysmorphisms are independent predictors of pathogenic copy number variants: a retrospective study on array-CGH results and phenotypical features of 293 children with neurodevelopmental disorders and/or multiple congenital anomalies.

Italian journal of pediatrics·2018
Same author

A novel risk score for severe ARDS patients undergoing ECMO after retrieval from peripheral hospitals.

Acta anaesthesiologica Scandinavica·2017
Same author

Diagnostic application of a capture based NGS test for the concurrent detection of variants in sequence and copy number as well as LOH.

Clinical genetics·2017
Same journal

[Bronchiectasis worsening by p-ANCA (bactericidal/permeability-increasing protein) positive vasculitis. A case report and review of the literature].

Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna·2006
Same journal

[Celiac disease in the elderly: a case report].

Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna·2006
Same journal

Severe bleeding in a case of acquired factor VIII inhibitor associated with generalized pustular psoriasis.

Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna·2006
Same journal

Soft tissue infection caused by Mycobacterium chelonae following a liposculpture and lipofilling procedure.

Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna·2006
Same journal

[Characteristics of patients admitted to a Division of Internal Medicine. Is hospital the best setting of care?].

Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna·2006
Same journal

[Depression in patients with cardiovascular disease].

Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna·2006
See all related articles

Brain natriuretic peptide (BNP) is a cardiac hormone that regulates blood pressure and fluid balance. Elevated BNP levels indicate cardiovascular disease, making it a key prognostic marker.

Area of Science:

  • Cardiovascular Physiology
  • Endocrinology
  • Nephrology

Context:

  • Brain natriuretic peptide (BNP) is a hormone produced by the heart, similar in function to atrial natriuretic peptide (ANP).
  • BNP influences diuretic, natriuretic, hypotensive, and smooth muscle relaxant activities via natriuretic peptide receptors and cyclic GMP.
  • BNP exhibits a longer half-life than ANP due to lower affinity for clearance receptors and reduced susceptibility to degradation.

Purpose:

  • To elucidate the physiological and pathophysiological roles of Brain Natriuretic Peptide (BNP).
  • To investigate the mechanisms underlying BNP's effects on cardiovascular homeostasis.
  • To establish BNP's utility as a diagnostic and prognostic marker in cardiovascular diseases.

Summary:

  • BNP is synthesized primarily by the left ventricle and released in response to stimuli like increased arterial pressure and ventricular hypertrophy/dilation.

Related Experiment Videos

  • In the kidneys, BNP enhances glomerular filtration rate, inhibits sodium reabsorption, and suppresses renin-aldosterone release.
  • Plasma BNP levels are low in healthy individuals but significantly elevated in conditions such as heart failure, hypertension, and renal failure, serving as a prognostic index.

    • Impact:

    • BNP administration influences cardiovascular homeostasis, particularly sodium excretion and the renin-aldosterone axis.
    • Understanding BNP's role is crucial for managing cardiovascular diseases like congestive heart failure.
    • BNP levels serve as a reliable prognostic indicator in various cardiovascular and renal disease states.