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No association detected between a D3 receptor gene-expressed variant and schizophrenia
L G Rothschild1, J Badner, A Cravchik
1Clinical Neurogenetics Branch, National Institute of Mental Health, Bethesda, Maryland 20892-1274, USA.
American Journal of Medical Genetics
|April 9, 1996
Abstract:
A missense polymorphism (glycine to serine) in the first exon of the dopamine D3 (DRD3) gene was examined in the sib-pairs schizophrenia collection by the transmission test for linkage disequilibrium (TDT). No association due to linkage disequilibrium was detected using TDT. Additionally, no evidence for excess homozygosity was found.