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Myopic regression after photorefractive keratectomy
1Department of Ophthalmology, Kangnam St. Mary's Hospital, Catholic University Medical College, Seoul, Korea.
Summary
Myopic photorefractive keratectomy (PRK) can lead to myopic regression, especially in high myopia cases with full correction. Reducing the correction amount may decrease regression incidence in high myopia.
Area of Science:
- Ophthalmology
- Refractive Surgery
- Corneal Surgery
Background:
- Myopic photorefractive keratectomy (PRK) effectively corrects myopia but can cause complications like myopic regression.
- Myopic regression is a common, progressive complication that reduces uncorrected visual acuity.
Purpose of the Study:
- To evaluate the incidence and factors influencing myopic regression after PRK.
- To compare myopic regression rates across different degrees of myopia and correction levels.
Main Methods:
- Retrospective analysis of 228 eyes undergoing myopic PRK with the Summit excimer laser.
- Eyes were grouped by preoperative myopia degree and correction strategy (full vs. partial).
- Statistical analysis included regression formulas and Kaplan-Meier survival analysis.
Main Results:
- Myopic regression (>1.00 D) occurred in 40.5% (moderate myopia, full correction), 83.3% (high myopia, full correction), and 18.2% (high myopia, partial correction).
- The amount of correction significantly correlated with myopic regression (r=0.78, P<0.001).
- Cumulative regression hazard was higher in high myopia with full correction compared to moderate myopia with full correction.
Conclusions:
- Myopic regression incidence and amount depend on the correction level.
- Higher preoperative myopia may reduce regression if the correction amount is consistent.
- Further research on PRK with a 6.0 mm optical zone is needed to understand myopia and profile effects on regression.