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Updated: Aug 17, 2026

Generation of Shear Adhesion Map Using SynVivo Synthetic Microvascular Networks
Published on: May 25, 2014
The significance of adhesion molecules in nephrology
K Burkhardt1, G Hillebrand, A Bösnecker
1Department of Nephrology, University of Munich, Germany.
Abstract:
Our knowledge of adhesion molecules has exploded over the last 5 years and has swamped most fields of medicine including nephrology. This is not surprising because adhesion molecules play a pivotal role in all aspects of cell to cell contact. Thus, they are involved in important issues, such as fetal development, in any kind of inflammatory or immune response including allograft rejection, as well as thrombus formation, and in tumor growth and metastasis (1-3). This short overview briefly reports some aspects of the biology of relevant adhesion molecules and their significance in inflammatory kidney diseases and in hemodialysis and renal allograft rejection. Finally, new therapeutic opportunities that arise by blocking adhesion molecule function are discussed.
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