Related Experiment Videos
Fulminant 2-chlorodeoxyadenosine-related peripheral neuropathy in a patient with paraneoplastic neurological syndrome
K Warzocha1, E Krykowksi, J Góra-Tybor
12nd Department of Internal Medicine, Medical University of Lódź, Copernicus Hospital, Poland.
Leukemia & Lymphoma
|April 1, 1996
Abstract:
2-chlorodeoxyadenosine (2-CdA) has been demonstrated to be a neurotoxic agent when used at significantly greater doses than currently recommended for clinical use. In this report we describe a case of a 37-years-old man lymphoplasmacytoid malignant lymphoma and pre-existing paraneoplastic neurological syndrome who died of an apparent rapidly progressive sensorimotor peripheral neuropathy after completing treatment with two courses of low-doses of 2-CdA.