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Updated: Aug 12, 2026

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Mouse Eye Enucleation for Remote High-throughput Phenotyping
Published on: November 19, 2011
Transgenic mice: models for the study of cataractogenesis. A minireview
H Bloemendal1, E L Benedetti, I Dunia
1Department of Biochemistry, University of Nijmegen, The Netherlands.
Ophthalmic Research
|January 1, 1996
Abstract:
Genetic manipulation followed by (over)expression of the transgene product in lens tissue results in: (I) inhibition of denucleation of lens fibers; (II) interference with lens cell differentiation; (III) cataract formation. The events reviewed are preceded by membrane damage, perturbed assembly of the IF cytoskeleton and distortion of the cytoskeleton-membrane complex.

