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The collectins in innate immunity
J Epstein1, Q Eichbaum, S Sheriff
1Department of Pediatrics, Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Current Opinion in Immunology
|February 1, 1996
Abstract:
The collectins are proteins with collagen tails and globular lectin domains that appear to play an important role in mammalian first line host defense. Recent insights have clarified the structural basis of ligand recognition, the interactions of collectins with complement cascades, and the association with disease susceptibility.