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The normal menopause transition: an overview

S M McKinlay1

  • 1New England Research Institutes, Inc., Watertown, MA 02172, USA.

Maturitas
|March 1, 1996
PubMed
Summary
This summary is machine-generated.

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The median age of natural menopause for Caucasian women is 50-51 years. Smoking is the only factor identified that significantly impacts menopause timing, advancing it by 1.5-2 years.

Area of Science:

  • Reproductive Endocrinology
  • Epidemiology of Menopause

Background:

  • Menopause is a significant life stage with evolving research.
  • Understanding the timing and factors influencing menopause is crucial for women's health.

Purpose of the Study:

  • To establish a reliable knowledge base on menopause using population-based studies.
  • To identify key knowledge gaps in current menopause research.

Main Methods:

  • Systematic review of original research reports on menopause.
  • Assessment of the reliability and contribution of each study.
  • Focus on definition, age at menopause, transition factors, and concurrent physiological changes.

Main Results:

  • Median age of natural menopause in Caucasian women is 50-51 years.

Related Experiment Videos

  • Cigarette smoking is associated with an earlier menopause (1.5-2 years sooner).
  • No other factors showed an independent effect on age at menopause; no secular trend observed.

    • Conclusions:

    • Reliable data on menopause age in non-industrialized populations and diverse ethnic groups are lacking.
    • Further research is needed on perimenopause and cross-cultural perceptions of menopause.
    • There is a need for multi-disciplinary prospective data to link menopause-related processes.