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[Sural nerve biopsy in myotonic muscular dystrophy]
G R De Freitas1, M R De Freitas, O J Nascimento
1Serviço de Neurologia da Faculdade de Medicina da Universidade Federal Fluminense, Brasil.
Arquivos De Neuro-Psiquiatria
|March 1, 1996
Abstract:
Twelve patients with myotonic dystrophy were studied to look for the involvement of the peripheral nervous system in this disease. All of them showed the main signs and symptoms of the disease. They did not have another causes to justify a polineuropathy. They were submitted to sural nerve biopsy with counting of myelinated fibers and histogram. Patients showed a reduction in the number of myelinated fibers and in two patients the histogram was unimodal. We concluded that polineuropathy may be another multisystemic manifestation of myotonic dystrophy.