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The reactivity of B12 cofactors: the proteins make a difference
M L Ludwig1, C L Drennan, R G Matthews
1Department of Biological Chemistry and Biophysics, University of Michigan, Ann Arbor 48109-1055, USA.
Structure (London, England : 1993)
|May 15, 1996
Abstract:
Determination of the structure of intact methylmalonyl-CoA mutase from Propionibacterium shermanii, and comparisons with the structure of the cobalamin-binding fragment of methionine synthase from Escherichia coli, afford a first glimpse at the similarities and distinctions between the two principal classes of B12-dependent enzymes: the mutases and the methyltransferases.