Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chromosomal anomalies in cryptorchidism

I Sasagawa1, T Nakada, M Ishigooka

  • 1Department of Urology, Yamagata University, Japan.

International Urology and Nephrology
|January 1, 1996
PubMed
Summary

Chromosome analysis in 160 cryptorchidism patients revealed anomalies in 4.4%. This suggests routine chromosomal analysis for both bilateral and unilateral cryptorchidism cases is advisable to detect potential genetic links.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

P33-fine structural and immunohistochemical observations of the collar enamel in Lepisosteus and Polypterus, actinopterygian fish.

Bulletin du Groupement international pour la recherche scientifique en stomatologie & odontologie·2012
Same author

Fine structural and immunohistochemical detection of collar enamel in the teeth of Polypterus senegalus, an actinopterygian fish.

Cell and tissue research·2012
Same author

Treatment of rat bladder cancer with electrochemotherapy in vivo.

Methods in molecular medicine·2011
Same author

Therapeutic and prognostic value of chromosomal AP classification at the blastic phase of Ph-positive chronic myeloid leukemia: comparison of data from Nagasaki University, Japan and Roswell Park Memorial Institute, U.S.A.

Leukemia & lymphoma·2011
Same author

[Extrapleural pneumonectomy for malignant pleural mesothelioma].

Kyobu geka. The Japanese journal of thoracic surgery·2004
Same author

Successful treatment of retrograde ejaculation with amezinium.

Archives of andrology·2003

Area of Science:

  • Medical Genetics
  • Pediatric Endocrinology

Background:

  • Cryptorchidism, the failure of one or both testes to descend, is a common congenital condition.
  • Genetic factors are implicated in the etiology of cryptorchidism, but the precise contribution requires further elucidation.

Purpose of the Study:

  • To investigate the frequency and types of chromosomal abnormalities in patients diagnosed with cryptorchidism.
  • To determine if the laterality of cryptorchidism (unilateral vs. bilateral) correlates with the incidence of chromosomal anomalies.

Main Methods:

  • Karyotyping was performed on 160 patients presenting with cryptorchidism.
  • Patient data regarding laterality and presence of additional congenital anomalies were recorded.

Main Results:

Related Experiment Videos

  • Chromosomal anomalies were identified in 7 out of 160 patients (4.4%).
  • The incidence of chromosomal abnormalities did not significantly differ between unilateral and bilateral cryptorchidism.
  • Identified anomalies included sex chromosomal aberrations, marker chromosomes, and autosomal anomalies.
  • Additional congenital anomalies were noted in a subset of patients with chromosomal aberrations.

Conclusions:

  • The findings support the recommendation for routine chromosome analysis in all patients diagnosed with cryptorchidism, irrespective of laterality.
  • Chromosome analysis may aid in identifying underlying genetic conditions and associated anomalies in cryptorchidism patients.