Related Experiment Videos
Human insulin-induced lipoatrophy. Successful treatment using a jet-injection device
Objective:
To evaluate the efficacy of the administration of insulin by a jet-injector device in stopping and reversing severe human insulin-induced lipoatrophy.
Case:
We report a case of a woman with severe human insulin-induced lipoatrophy who has been treated exclusively with recombinant DNA human insulin since the onset of IDDM.
Results:
The loss of subcutaneous tissue in the injection areas was demonstrated and measured by high-frequency ultrasound. Dermatologic exam demonstrated a severe reduction of fat tissue. After 8 months of administration of human insulin by a jet injector, there were no more new lesions of lipoatrophy and those affected areas were substantially ameliorated.
Conclusions:
Jet-injection devices might constitute a helpful method to treat those patients affected by severe human insulin-induced lipoatrophy.