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Improvement of debilitating tardive dyskinesia with risperidone
S R Rangwani1, S Gupta, W J Burke
1Creighton-Nebraska Department of Psychiatry, Omaha 68198-5575, USA.
Summary
Low-dose risperidone significantly improved tardive dyskinesia (TD) in an elderly patient with a history of neuroleptic use. The patient remained symptom-free at one year, suggesting risperidone
Area of Science:
- Neurology
- Psychiatry
Background:
- Tardive dyskinesia (TD) is a movement disorder associated with long-term neuroleptic medication.
- Elderly patients with extensive neuroleptic exposure are particularly vulnerable to developing TD.
Observation:
- A case vignette details an elderly female patient with a history of neuroleptic exposure and diagnosed TD.
- The patient was treated with a low dose of risperidone.
Findings:
- The patient experienced a dramatic improvement in TD symptoms following risperidone treatment.
- TD remission was sustained for a one-year follow-up period.
Implications:
- This case suggests low-dose risperidone may be an effective treatment for tardive dyskinesia.
- Further randomized controlled trials are warranted to confirm the efficacy of risperidone in managing TD.