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Bilateral primary seminal vesicle carcinoma
A H Ormsby1, R Haskell, S E Ruthven
1Department of Anatomical Pathology, Gosford Hospital, NSW.
Pathology
|May 1, 1996
Summary
This report details a rare case of bilateral primary seminal vesicle carcinoma in a 73-year-old man. This finding highlights the importance of considering rare cancers in diagnosis and treatment.
Area of Science:
- Urology
- Oncology
- Pathology
Background:
- Primary seminal vesicle carcinoma is an exceptionally rare malignancy.
- Fewer than 50 cases of primary seminal vesicle neoplasia have been histologically confirmed globally.
- Bilateral involvement is even rarer, with only four previously reported cases.
Observation:
- A 73-year-old Australian man presented with a tumor localized to both seminal vesicles and the adjacent right prostate lobe.
- Histological examination revealed a well-differentiated papillary adenocarcinoma, negative for PSA, PAP, and CEA.
- The tumor morphology resembled normal seminal vesicle epithelium, with no evidence of other primary carcinomas.
Findings:
- The patient was diagnosed with bilateral primary seminal vesicle carcinoma.
- Metastases also exhibited the same histological characteristics and immunophenotype.
- The patient achieved a disease-free survival of over three years post-diagnosis.
Implications:
- This case underscores the diagnostic challenges associated with seminal vesicle tumors due to difficulties in clinical and radiological detection.
- Discussion includes pathological criteria for diagnosing primary seminal vesicle carcinoma.
- The role of CA-125 immunoreactivity in diagnosis warrants further investigation.