Related Experiment Videos
Sternum length and intermammillary distance in normal newborns
Journal De Genetique Humaine
|March 1, 1977
Summary
Short sternum and widely spaced nipples are key indicators in several genetic syndromes. Measuring sternum length and intermammillary distance in newborns can aid in phenotypic descriptions of these conditions.
Area of Science:
- Medical genetics
- Human anatomy
- Pediatric diagnostics
Background:
- Short sternum and widely spaced nipples are recognized clinical findings in various genetic syndromes.
- These findings are associated with Edwards' syndrome, Patau's syndrome, Noonan syndrome, Turner syndrome, and renal hypoplasia syndromes.
Purpose of the Study:
- To investigate the relationship between sternum length and intermammillary distance in newborns.
- To determine the utility of these measurements in the phenotypic description of genetic syndromes.
Main Methods:
- Measurements of sternum length, intermammillary distance, trunk length, and thoracic circumference were taken.
- Data was collected from 307 consecutive live newborns.
- Statistical analysis, including partial regression, was performed.
Main Results:
- Intermammillary distance showed the highest partial regression coefficient over sternum length.
- This indicates a significant relationship between these two anthropometric parameters.
Conclusions:
- Both sternum length and intermammillary distance are important parameters for phenotypic descriptions.
- Considering both measurements is advisable when abnormal variations are suspected in genetic syndromes.