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Alteration of visual function in impaired glucose tolerance
S Karadeniz1, N Kir, M T Yilmaz
1Institute for Experimental Medicine, Istanbul University, Turkey.
European Journal of Ophthalmology
|January 1, 1996
Summary
Individuals with impaired glucose tolerance show altered color vision and contrast sensitivity, potentially predicting future diabetes. These visual function changes may indicate early diabetic retinopathy risk.
Area of Science:
- Ophthalmology
- Endocrinology
- Visual Science
Background:
- Impaired glucose tolerance (IGT) is a precursor to type 2 diabetes.
- Visual function changes may precede clinical diagnosis of diabetes.
Purpose of the Study:
- To investigate color vision and contrast sensitivity in individuals with IGT.
- To compare visual function between normal glucose tolerance (NGT), IGT, and type 2 diabetes (NIDDM) groups.
- To assess the predictive value of visual alterations for diabetes development.
Main Methods:
- Farnsworth-Munsell 100 Hue test for color vision.
- Arden's grating cards for contrast sensitivity.
- Exclusion of participants with low vision or ocular abnormalities.
Main Results:
- Significant differences in contrast sensitivity and color vision were observed between NGT, IGT, and NIDDM groups (p < 0.01).
- Visual function alterations were present in individuals with IGT before clinical diabetes diagnosis.
Conclusions:
- IGT is associated with measurable changes in color vision and contrast sensitivity.
- These visual function alterations may serve as early indicators for diabetes and diabetic retinopathy risk.
- Longitudinal studies are warranted to confirm the predictive value of these findings.